Le germe de blé peut être envisagé sous forme de cure de 2 mois en automne et au printemps à la dose de 1 à 2 cuillères à café par jour, le matin.
Le germe de blé a une teneur élevée en oligoéléments et sels minéraux, en particulier en phosphore, magnésium, vitamines du groupe B, vitamines E (antioxydante) et D (antirachitique et antiostéoporotique).
Les jeunes femmes ménopausées peuvent prendre une cuillère à café entre l’automne et la fin du printemps.

Le germe de blé fermenté est également un anticancéreux naturel, un tonique général ; il est efficace dans les anémies, la déminéralisation osseuse, les maladies cardiovasculaires et certains troubles psychiques.

Références

• Farkas E. Fermented wheat germ extract in the supportive therapy of colorectal cancer Orv Hetil. 2005 Sep 11 ;146(37):1925-31.
• Jakab F, Shoenfeld Y, Balogh A, Nichelatti M, Hoffmann A, Kahan Z, Lapis K, Mayer A, Sapy P, Szentpetery F, Telekes A, Thurzo L, Vagvolgyi A, Hidvegi M. A medical nutriment has supportive value in the treatment of colorectal cancer. Br J Cancer. 2003 Aug 4 ;89(3):465-9.
• Hidvegi M, Raso E, Tomoskozi-Farkas R, Szende B, Paku S, Pronai L, Bocsi J, Lapis K. MSC, a new benzoquinone-containing natural product with antimetastatic effect. Cancer Biother Radiopharm. 1999 Aug ;14(4):277-89.

• Garami M, Schuler D, Babosa M, Borgulya G, Hauser P, Muller J, Paksy A, Szabo E, Hidvegi M, Fekete G. Fermented wheat germ extract reduces chemotherapy-induced febrile neutropenia in pediatric cancer patients. J Pediatr Hematol Oncol. 2004 Oct ;26(10):631-5.

• Jakab F, Mayer A, Hoffmann A, Hidvegi M. First clinical data of a natural immunomodulator in colorectal cancer. Hepatogastroenterology. 2000 Mar-Apr ;47(32):393-5.

• Hidvegi M, Raso E, Tomoskozi-Farkas R, Paku S, Lapis K, Szende B. Effect of Avemar and Avemar + vitamin C on tumor growth and metastasis in experimental animals.Anticancer Res. 1998 Jul-Aug ;18(4A):2353-8.

• Comin-Anduix B, Boros LG, Marin S, Boren J, Callol-Massot C, Centelles JJ, Torres JL, Agell N, Bassilian S, Cascante M. Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells. J Biol Chem. 2002 Nov 29 ;277(48):46408-14. Epub 2002 Sep 25.

• Balint G, Apathy A, Gaal M, Telekes A, Resetar A, Blazso G, Falkay G, Szende B, Paksy A, Ehrenfeld M, Shoenfeld Y, Hidvegi M. Effect of Avemar—a fermented wheat germ extract—on rheumatoid arthritis. Preliminary data. Clin Exp Rheumatol. 2006 May-Jun ;24(3):325-8.

• Bock PR, Friedel WE, Hanisch J, Karasmann M, Schneider B. Efficacy and safety of long-term complementary treatment with standardized European mistletoe extract (Viscum album L.) in addition to the conventional adjuvant oncologic therapy in patients with primary non-metastasized mammary carcinoma. Results of a multi-center, comparative, epidemiological cohort study in Germany and Switzerland Arzneimittelforschung. 2004 ;54(8):456-66. German. Erratum in : Arzneimittelforschung. 2004 ;54(9):563.

• Cazacu M, Oniu T, Lungoci C, Mihailov A, Cipak A, Klinger R, Weiss T, Zarkovic N. The influence of isorel on the advanced colorectal cancer. Cancer Biother Radiopharm. 2003 Feb ;18(1):27-34.

• Popiela T, Kulig J, Hanisch J, Bock PR. Influence of a complementary treatment with oral enzymes on patients with colorectal cancers—an epidemiological retrolective cohort study. Cancer Chemother Pharmacol. 2001 Jul ;47 Suppl:S55-63.
• Fajka-Boja R, Hidvegi M, Shoenfeld Y, Ion G, Demydenko D, Tomoskozi-Farkas R, Vizler C, Telekes A, Resetar A, Monostori E. Fermented wheat germ extract induces apoptosis and downregulation of major histocompatibility complex class I proteins in tumor T and B cell lines. Int J Oncol. 2002 Mar ;20(3):563-70.

• Inoue Y, Miki C, Hiro J, Ojima E, Yamakado K, Takeda K, Kusunoki M. Improved survival using multi-modality therapy in patients with lung metastases from colorectal cancer : a preliminary study. Oncol Rep. 2005 Dec ;14(6):1571-6.

• Illmer C, Madlener S, Horvath Z, Saiko P, Losert A, Herbacek I, Grusch M, Krupitza G, Fritzer-Szekeres M, Szekeres T. Immunologic and biochemical effects of the fermented wheat germ extract Avemar. Exp Biol Med (Maywood). 2005 Feb ;230(2):144-9.

• Boros LG, Nichelatti M, Shoenfeld Y. Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases. Ann N Y Acad Sci. 2005 Jun ;1051:529-42. Review.

• Valentini V, Morganti AG, Gambacorta MA, Mohiuddin M, Doglietto GB, Coco C, De Paoli A, Rossi C, Di Russo A, Valvo F, Bolzicco G, Dalla Palma M ; Study Group for Therapies of Rectal Malignancies (STORM). Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis : A multicentric phase II study. Int J Radiat Oncol Biol Phys. 2006 Mar 15 ;64(4):1129-39.

• Schumacher K, Schneider B, Reich G, Stiefel T, Stoll G, Bock PR, Hanisch J, Beuth J. Influence of postoperative complementary treatment with lectin-standardized mistletoe extract on breast cancer patients. A controlled epidemiological multicentric retrolective cohort study. Anticancer Res. 2003 Nov-Dec ;23(6D):5081-7.

• Saiko P, Ozsvar-Kozma M, Madlener S, Bernhaus A, Lackner A, Grusch M, Horvath Z, Krupitza G, Jaeger W, Ammer K, Fritzer-Szekeres M, Szekeres T. Avemar, a nontoxic fermented wheat germ extract, induces apoptosis and inhibits ribonucleotide reductase in human HL-60 promyelocytic leukemia cells. Cancer Lett. 2007 Jun 8 ;250(2):323-8. Epub 2006 Nov 29.